iLIR v1.0 WWW Server: RESULTS PAGE

Submitted 1 sequence
>sp|Q00610|CLH1_HUMAN Clathrin heavy chain 1 OS=Homo sapiens GN=CLTC PE=1 SV=5

{"length":"1675","regions":[{
startStyle: "curved", endStyle: "curved",
start: 19, end: 56, text: "Pfam:Clathrin_propel", colour: "#ff8800",
"metadata":{ database: "PFAM", type: "Pfam:Clathrin_propel",
description: "Pfam:Clathrin_propel", start: 19, end: 56}
},
{
startStyle: "curved", endStyle: "curved",
start: 148, end: 187, text: "Pfam:Clathrin_propel", colour: "#ff8800",
"metadata":{ database: "PFAM", type: "Pfam:Clathrin_propel",
description: "Pfam:Clathrin_propel", start: 148, end: 187}
},
{
startStyle: "curved", endStyle: "curved",
start: 198, end: 234, text: "Pfam:Clathrin_propel", colour: "#ff8800",
"metadata":{ database: "PFAM", type: "Pfam:Clathrin_propel",
description: "Pfam:Clathrin_propel", start: 198, end: 234}
},
{
startStyle: "curved", endStyle: "curved",
start: 331, end: 354, text: "Pfam:Clathrin-link", colour: "#ff8800",
"metadata":{ database: "PFAM", type: "Pfam:Clathrin-link",
description: "Pfam:Clathrin-link", start: 331, end: 354}
},
{
startStyle: "straight", endStyle: "straight",
start: 445, end: 458, text: "LCR", colour: "#86bcff",
"metadata":{ database: "INTRINSIC", type: "low_complexity_region",
description: "LCR", start: 445, end: 458}
},
{
startStyle: "curved", endStyle: "curved",
start: 537, end: 679, text: "CLH", colour: "#ff8800",
"metadata":{ database: "SMART", type: "CLH",
description: "CLH", start: 537, end: 679}
},
{
startStyle: "curved", endStyle: "curved",
start: 686, end: 828, text: "CLH", colour: "#ff8800",
"metadata":{ database: "SMART", type: "CLH",
description: "CLH", start: 686, end: 828}
},
{
startStyle: "curved", endStyle: "curved",
start: 833, end: 972, text: "CLH", colour: "#ff8800",
"metadata":{ database: "SMART", type: "CLH",
description: "CLH", start: 833, end: 972}
},
{
startStyle: "curved", endStyle: "curved",
start: 979, end: 1124, text: "CLH", colour: "#ff8800",
"metadata":{ database: "SMART", type: "CLH",
description: "CLH", start: 979, end: 1124}
},
{
startStyle: "curved", endStyle: "curved",
start: 1128, end: 1269, text: "CLH", colour: "#ff8800",
"metadata":{ database: "SMART", type: "CLH",
description: "CLH", start: 1128, end: 1269}
},
{
startStyle: "curved", endStyle: "curved",
start: 1274, end: 1420, text: "CLH", colour: "#ff8800",
"metadata":{ database: "SMART", type: "CLH",
description: "CLH", start: 1274, end: 1420}
},
{
startStyle: "curved", endStyle: "curved",
start: 1423, end: 1582, text: "CLH", colour: "#ff8800",
"metadata":{ database: "SMART", type: "CLH",
description: "CLH", start: 1423, end: 1582}
},
{
startStyle: "straight", endStyle: "straight",
start: 1662, end: 1673, text: "LCR", colour: "#86bcff",
"metadata":{ database: "INTRINSIC", type: "low_complexity_region",
description: "LCR", start: 1662, end: 1673}
},
{
startStyle: "straight", endStyle: "straight",
start: 512, end: 517, text: "xLIR", colour: "#ff00ff",
lineStyle: "bold", v_align: "top", label: "xLIR",
"metadata":{ database: "xLIR web server", type: "xLIR-motif",
description: "xLIR-motif:PDWIFL", start: 512, end: 517}
},
{
startStyle: "straight", endStyle: "straight",
start: 1315, end: 1320, text: "xLIR", colour: "#ff00ff",
lineStyle: "bold", v_align: "top", label: "xLIR",
"metadata":{ database: "xLIR web server", type: "xLIR-motif",
description: "xLIR-motif:GMFTEL", start: 1315, end: 1320}
},
{
startStyle: "straight", endStyle: "straight",
start: 1475, end: 1480, text: "xLIR", colour: "#ff00ff",
lineStyle: "bold", v_align: "top", label: "xLIR",
"metadata":{ database: "xLIR web server", type: "xLIR-motif",
description: "xLIR-motif:EDYQAL", start: 1475, end: 1480}
},
]
}

xLIR motifs are displayed as magenta rectangles in the domain architecture graphic

MOTIF	START	END	LIR sequence	PSSM score	Similar LIRs	In PDB	Anchor
xLIR	512	517	PDWIFL	22 (4.4e-03)	CALR_HUMAN 198-203 (4) CLH1_HUMAN 512-517 (6)	[+/-] 3IYV_A,B,C,D,E,F,G,H,I 1XI5_A,B,C,D,E,F,G,H,I 3IYV_A,B,C,D,E,F,G,H,I 1XI5_A,B,C,D,E,F,G,H,I 1XI4_A,B,C,D,E,F,G,H,I	No
xLIR	1315	1320	GMFTEL	11 (1.5e-01)		[+/-] 3IYV_A,B,C,D,E,F,G,H,I 1XI5_A,B,C,D,E,F,G,H,I 3IYV_A,B,C,D,E,F,G,H,I 1XI5_A,B,C,D,E,F,G,H,I 1XI4_A,B,C,D,E,F,G,H,I 3LVH_A,B,C 3LVG_A,B,C 1B89_A	No
xLIR	1475	1480	EDYQAL	16 (3.0e-02)		[+/-] 3IYV_A,B,C,D,E,F,G,H,I 1XI5_A,B,C,D,E,F,G,H,I 3IYV_A,B,C,D,E,F,G,H,I 1XI5_A,B,C,D,E,F,G,H,I 1XI4_A,B,C,D,E,F,G,H,I 3LVH_A,B,C 3LVG_A,B,C 1B89_A	No

No ANCHORs detected ...

[+/-] Show/Hide Detailed SMART results

DOMAIN	START	END	E-VALUE	TYPE	STATUS
Pfam:Clathrin_propel	19	56	8.6e-08	PFAM	visible\|OK
Pfam:Clathrin_propel	148	187	1.5e-09	PFAM	visible\|OK
Pfam:Clathrin_propel	198	234	1.7e-09	PFAM	visible\|OK
Pfam:Clathrin-link	331	354	4.8e-17	PFAM	visible\|OK
low_complexity_region	445	458	0	INTRINSIC	visible\|OK
SMART:CLH	537	679	1.6e-41	SMART	visible\|OK
Pfam:Clathrin	537	679	2.6e-25	PFAM	hidden\|overlap
SMART:CLH	686	828	1.2e-45	SMART	visible\|OK
Pfam:Clathrin	686	827	6.8e-29	PFAM	hidden\|overlap
SMART:CLH	833	972	6.7e-42	SMART	visible\|OK
Pfam:Clathrin	833	971	8.1e-32	PFAM	hidden\|overlap
SMART:CLH	979	1124	7.2e-47	SMART	visible\|OK
Pfam:Clathrin	979	1123	2.9e-37	PFAM	hidden\|overlap
SMART:CLH	1128	1269	2.4e-44	SMART	visible\|OK
Pfam:Clathrin	1128	1268	8.1e-33	PFAM	hidden\|overlap
SMART:CLH	1274	1420	3.4e-48	SMART	visible\|OK
Pfam:Clathrin	1274	1419	3.7e-36	PFAM	hidden\|overlap
SMART:CLH	1423	1582	8.4e-43	SMART	visible\|OK
Pfam:Clathrin	1423	1565	3.0e-34	PFAM	hidden\|overlap
low_complexity_region	1662	1673	0	INTRINSIC	visible\|OK