iLIR v1.0 WWW Server: RESULTS PAGE

Submitted 1 sequence
>sp|Q13043|STK4_HUMAN Serine/threonine-protein kinase 4 OS=Homo sapiens GN=STK4 PE=1 SV=2

{"length":"487","regions":[{
startStyle: "curved", endStyle: "curved",
start: 30, end: 281, text: "S_TKc", colour: "#ff8800",
"metadata":{ database: "SMART", type: "S_TKc",
description: "S_TKc", start: 30, end: 281}
},
{
startStyle: "straight", endStyle: "straight",
start: 311, end: 326, text: "LCR", colour: "#86bcff",
"metadata":{ database: "INTRINSIC", type: "low_complexity_region",
description: "LCR", start: 311, end: 326}
},
{
startStyle: "curved", endStyle: "curved",
start: 432, end: 480, text: "Pfam:Mst1_SARAH", colour: "#ff8800",
"metadata":{ database: "PFAM", type: "Pfam:Mst1_SARAH",
description: "Pfam:Mst1_SARAH", start: 432, end: 480}
},
{
startStyle: "straight", endStyle: "straight",
start: 28, end: 33, text: "xLIR", colour: "#ff00ff",
lineStyle: "bold", v_align: "top", label: "xLIR",
"metadata":{ database: "xLIR web server", type: "xLIR-motif",
description: "xLIR-motif:EVFDVL", start: 28, end: 33}
},
{
startStyle: "straight", endStyle: "straight",
start: 431, end: 436, text: "xLIR", colour: "#ff00ff",
lineStyle: "bold", v_align: "top", label: "xLIR",
"metadata":{ database: "xLIR web server", type: "xLIR-motif",
description: "xLIR-motif:GDYEFL", start: 431, end: 436}
},
]
}

xLIR motifs are displayed as magenta rectangles in the domain architecture graphic

MOTIF	START	END	LIR sequence	PSSM score	Similar LIRs	In PDB	Anchor
xLIR	28	33	EVFDVL	9 (2.8e-01)		[+/-] 3COM_A,B 4LG4_A,B,C,D,E,F 3COM_A,B 4LG4_A,B,C,D,E,F 3A7H_A,B 1UA2_A,B,C,D 3GU7_A 3GU6_A 3GU5_A 3GU4_A 3PJC_A 3LXL_A 3LXK_A 1YVJ_A 3KCK_A 3IOK_A 3IO7_A 4CJY_C,D 3JY9_A 2JAM_A,B 4I6Q_A 4HVI_A 4HVH_A 4HVG_A 4HVD_A 4GL9_A,B,C,D 3ZEP_A,B,C,D 3ZC6_A,B,C,D 3GUB_A 3GU8_A 4GMY_A 4GFM_A 4F09_A 4F08_A,B 4E4M_A,B,D,E 3LPB_A,B 3KRR_A 4BL1_A 4BKZ_A 4BKY_A 2XA4_A,B 4AQC_A,B 3Q32_A,B 4JIA_A 4JI9_A,B 4IVA_A 4HGE_A,B 3TJD_A,B 3TJC_A,B 3FUP_A,B 2B7A_A,B 3RVG_A 3E64_A 3E63_A 3E62_A 2W1I_A,B 4C62_A,B 4C61_A,B 3ZMM_A,B 3UGC_A 3A7G_A,B 4BBF_A,B,C,D 4BBE_A,B,C,D 3A7F_A 4EJN_A 2X2M_A,B 2X2L_A 2X2K_A 2IVU_A 2IVT_A 2IVS_A,B 2PE2_A 2PE1_A 2PE0_A 1Z5M_A 3O96_A 3NUY_A 3NUU_A 3NUS_A 1UU9_A 1UVR_A 1H1W_A 2IVV_A 4IXP_A 4E6Q_A,B 4E6D_A,B 4B9D_A,B 4APC_A,B 2VZ6_A,B 3DK7_A,B 3GGF_A,B 1VZO_A 4G9R_A,B 4EHG_A,B 3IDP_A,B 1UWJ_A,B 3DK3_A,B 4G3G_A 4FK3_A,B 3A4O_X 4KSQ_A,B 4KSP_A,B 4H58_A,B,C 4FC0_A,B 4DBN_A,B 2FB8_A,B 3OG7_A,B 4FZF_B 3Q96_A,B 4J95_A,B,C,D 2PVY_A,B,C,D 3II5_A,B 4MBJ_A,B 4G9C_A,B 4EHE_A,B 4E4X_A,B 4E26_A,B 3TV6_A,B 3TV4_A,B 3SKC_A,B 3Q4C_A,B 3PSD_A,B 3PSB_A,B 3PRI_A,B 3PRF_A,B 3PPK_A,B 3PPJ_A,B 3D4Q_A,B 1UWH_A,B 4JVG_A,B,C,D 3C4C_A,B 3DK6_A,B 4G3F_A 3Q5I_A 4G3E_A,B 4G3C_A,B 2ZVA_A 2ZV9_A 2ZV8_A 2ZV7_A 3P1A_A 4J99_A,B,C,D 4FZD_B 4J98_A,B 2PZP_A,B 4J97_A,B,C,D 2PZ5_A,B 2PWL_A,B 4DFZ_E 1OEC_A 1GJO_A 3RI1_A,B 4DFX_E 3B2T_A,B 4J96_A,B 3CLY_A 4DG3_E 2PVF_A 2PSQ_A,B 2PZR_A,B 2GU8_A 4IB3_A 4FF8_A 4IB1_A 4FEQ_A 3QUP_A 4IB0_A 3KUL_A 3KUL_B 4FZA_B 4IAZ_A 4G5P_A,B 4IAY_A 4I24_A,B 3IKA_A,B 2JIU_A,B 2JIT_A,B 4IAK_A 2Q0B_A,B 2JIV_A,B 4IAI_A 4IAF_A 2PY3_A,B 4IAD_A 3TT0_A,B 4IAC_A 3QA8_A,B,C,D,E,F,G,H 3RZF_A 2HW6_A,B 4HPU_E 4HPT_E 4DIN_A 4I21_A,B 2X7F_A,B,C,D,E 4DH8_A 4DH7_A 4DH5_A 4DH3_A 3GQL_A,B,C 4DH1_A 4DG2_E 4DG0_E 3W2R_A 3W2Q_A 3W2P_A 3TNQ_B 3W2O_A 4KIK_A 4KIK_B 3TNP_C,F 3QAL_E 4BC6_A 3OW3_A 3O7L_D 3IDC_A 4I22_A 4I1Z_A 4LL0_A,B 3C4F_A,B 3GQI_A 2FGI_A,B 3IDB_A 1FGK_A,B 1FGI_A,B 1AGW_A,B 3KY2_A,B 3JS2_A,B 4NKS_A,B 4NKA_A,B 4NK9_A,B 4F65_A,B 4F64_A,B 3FJQ_E 4F63_A,B 3KXX_A,B,C,D 3RHX_A,B 2QVS_E 2QCS_A 3LZB_A,B,C,D,E,F,G,H 3BEL_A 2RGP_A 1M17_A 1M14_A 2CPK_E 3W33_A 3W32_A 3W2S_A 3VJO_A 2RF9_A,B 2GS6_A 2GS2_A 4LI5_A 3VJN_A 3UG2_A 1REK_A 3UG1_A 3FXW_A 3FHR_A 4G5J_A 4I23_A 3POZ_A 3GT8_A,B,C,D 2J6M_A 1REJ_A 2J5F_A 2J5E_A 2ITY_A 2ITX_A 2ITW_A 2GS7_A,B 4EQU_A,B 1RE8_A 4JRV_A 4JR3_A 4JQ8_A 4JQ7_A 1XKK_A 1L3R_E 3GOP_A 4HJO_A 3QC9_A,B,C,D 1TKI_A,B 3C51_A,B 3C50_A,B 1JLU_E 3C4Z_A 3C4Y_A,B 3C4X_A,B 3C4W_A,B 3T8O_A 4MXZ_A,B 4MXY_A,B 2SRC_A 1J3H_A,B 1Y57_A 1FMK_A 2RFE_A,B,C,D 2RFD_A,B 2EB3_A 2OG8_A,B 4L9I_A,B 1FMO_E 2ITZ_A 2ITV_A 2ITU_A 2ITT_A 2H8H_A 4I20_A 4LQM_A 3G6H_A,B 3DQW_A,B,C,D 3LOK_A,B 1BX6_A 3F3W_A,B 2QQ7_A,B 2QI8_A,B 3LCK_A 3BYO_A 2OF4_A 2OF2_A 1BKX_A 1RJB_A 3BYM_A 1KSW_A 2OFU_A 2BDJ_A 2BDF_A,B 1ATP_E 4MXO_A,B 1YI6_A,B 3U51_A,B 3U4W_A 4FIC_A,B 4DGG_A,B 4AGW_A,B 3UQG_A,B 3J4R_D,E 3UQF_A,B 3G6G_A,B 3F6X_A,B,C,D 3EN7_A,B 3EN6_A,B 3EN5_A,B 3EN4_A,B 3EL8_A,B 3EL7_A 3DQX_A,B 3J4Q_D,E 3D7T_B 2OIQ_A,B 3QLG_A,B 3QLF_A,B 3OF0_A,B 3OEZ_A,B 2EB2_A 3D7U_B,D 3SVV_A,B 4LGD_A,B,C,D 4AOT_A,B 2ERZ_E 2PTK_A 1JBP_E 2ITQ_A 2ITP_A 2ITO_A 2ITN_A 1QPJ_A 1QPE_A 1QPC_A 2QUR_A 3BYU_A 3BYS_A 3B2W_A 2OFV_A,B 3FHI_A 3KMM_A 2HW7_A 2AC5_A 4C3F_A 3MPM_A 1YOL_A,B 4MCV_A,B 4LGH_A,B 3PVB_A 1MUO_A 1APM_E 1YOM_A,B 1YOJ_A,B 2PL0_A 3KXZ_A 2J7T_A 3GEQ_A,B 3AD6_A 3AD5_A 3AD4_A 3ACK_A 3ACJ_A 3AC8_A 3AC5_A 3AC4_A 3AC3_A 3AC2_A 3AC1_A 2ZYB_A 2ZM4_A 2ZM1_A 1QPD_A 4ID7_A 2ZOQ_A,B 4HZR_A,B 3EQR_A,B 3EQP_A,B 4MXX_A,B 3TZ9_A,B 3TZ8_A,B 3TZ7_A,B 3G5D_A,B 3F3V_A,B 3F3U_A,B 3F3T_A,B 2QLQ_A,B 2HWP_A,B 2HWO_A,B 4EWH_A,B 1U54_A 1U54_B 4DFY_A,E 1U4D_A,B 1U46_A,B 3RCD_A,B,C,D 3PP0_A,B 4HZS_A,B,C,D 3VS7_A,B 3VS6_A,B 3VS5_A,B 3VS4_A,B 2J4Z_A,B 3VS3_A,B 3VS2_A,B 3VS1_A,B 3VS0_A,B 3VRZ_A,B 3VRY_A,B 2C0T_A,B 2C0O_A,B 2C0I_A,B 1QCF_A 2R4B_A,B 2UV2_A 2HK5_A 3BCE_A,B,C 3BBW_A,B 3BBT_B,D 4LRM_A,B,C,D,E 4O2Z_A 3ZBF_A 3CJG_A 3CJF_A 2AC3_A 2DQ7_X 2JFM_A 2HCK_A,B 1AD5_A,B 2OH4_A 3C7Q_A 3EFL_A,B 2P2I_A,B 4ASE_A 4ASD_A 4AGD_A 4AGC_A 4AG8_A 2XIR_A 1YWN_A 1VR2_A 3VO3_A 3VNT_A 3U6J_A 1O9U_A 3EWH_A 3DTW_A,B 3CPC_A,B 3CPB_A,B 3CP9_A,B 3BE2_A 3B8R_A,B 3B8Q_A,B 2RL5_A 2QU6_A,B 2QU5_A 2P2H_A 4HVS_A 4E7W_A 3GB2_A 3NYO_A,B 3NYN_A,B 4B7T_A 3ZDI_A 3SD0_A,B 3F7Z_A,B 2ACX_A,B 2OW3_A,B 1R0E_A,B 4ACH_A,B 4ACG_A,B 4ACD_A,B 4ACC_A,B 3ZRM_A,B 3ZRL_A,B 3ZRK_A,B 2JFL_A 1GNG_A,B 4DIT_A 4AFJ_A,B 2O5K_A 4IQ6_A,B 3Q3B_A,B 3L1S_A,B 3I4B_A,B 1Q5K_A,B 1Q4L_A,B 1Q41_A,B 1Q3W_A,B 1Q3D_A,B 4J71_A,B 4J1R_A,B,C,D 3SAY_A,B 3PUP_A,B 3M1S_A,B 2JLD_A,B 1J1C_A,B 1J1B_A,B 1I09_A,B 3DU8_A,B 1PYX_A,B 1H8F_A,B 1UV5_A 3F88_A,B 1T46_A 3G0F_A,B 1T45_A 3G0E_A 1PKG_A,B 1SYK_A,B 3E3P_A,B 3O7L_B 2Y4I_B 2J51_A 3RP9_A 3ZZW_A,B 1LUF_A 4F7S_A 4F7N_A 4F7L_A 4F7J_A 4F70_A 4F6W_A 4F6U_A 4F6S_A 3RGF_A 4GT4_A,B 4G6L_A 4AZF_A 3KVW_A 3K2L_A 4ANS_A 4ANQ_A 4ANL_A 2YHV_A 2YFX_A 2XBA_A 2XB7_A 2YJR_A 3BGZ_A 3BGQ_A 3BGP_A 2OBJ_A 4MWI_A 2XP2_A 4ALW_A 4ALV_A 2YJS_A 3L9N_A 4FNW_A 4JX7_A 4JX3_A 4M67_A 4BZO_A 4BZN_A 1XWS_A 1YXS_A 4N70_A 4N6Z_A 1YHW_A 3L9M_A,B 4N6Y_A 3T9I_A 3DCV_A 4FNY_A 4FNX_A 4FOD_A 4DCE_A,B 3A99_A 4FNZ_A 2XJ2_A 2XJ1_A 2XJ0_A 2XIZ_A 2XIY_A 2XIX_A 4F9C_A 4F9B_A,C 4F9A_A,C 4F99_A 4I41_A 4DTK_A 3F2A_A 1XR1_A 1XQZ_A 4A7C_A 3VC4_A 3VBY_A 3VBX_A 3VBW_A 3VBV_A 3VBT_A 3VBQ_A 3R04_A 3R02_A 3R01_A 3R00_A 2O65_A 2O64_A 2O63_A 2O3P_A 1YXX_A 1YXV_A 1YXU_A,B,C,D 1YXT_A 1YWV_A 4IAA_A 4ENY_A 4ENX_A 3UMX_A 3UMW_A 3UIX_A 4K1B_A 4K0Y_A 3C4E_A,B,C,D 1YI4_A 1YI3_A 1YHS_A 3AOX_A 4MBL_A 4MBI_A 4GW8_A 3QF9_A 3MA3_A 3JYA_A 3JY0_A 3JXW_A 3JPV_A 2J2I_B 4K18_A 4JOA_A 3LCT_A 3LCS_A 3BWF_A 2OI4_X 1RDQ_E 2C3I_B 2BZK_B 2BZJ_A 2BZI_B 2BZH_B 2BIL_B 2BIK_B 3CY3_A 3CY2_A 3CXW_A 3QAM_E 3L9P_A 4FOC_A 4FOB_A 4AS0_A 1F3M_C,D 3AMB_A 1NA7_A 2QLU_A 3AMA_A 4CKR_A 4BKJ_A,B 3ZOS_A,B 3BE9_A 2PVN_A 2PVM_A 2PVL_A 2PVK_A 2PVJ_A 2PVH_A 4DGN_A 4DGO_A 3KXN_A 3KXM_A 3KXH_A 3KXG_A 1M2R_A 1M2Q_A 4AE9_A,B 1M2P_A 1DAY_A 1DAW_A 4ANM_A 3PVG_A 3PZH_A 3PWD_A 3FL5_A 2QC6_A 2OXY_A,B 4AE6_A,B 2OXX_A 2OXD_A 1ZOH_A 1ZOG_A 1ZOE_A 1OM1_A 1LR4_A 1LPU_A 1LP4_A 1JAM_A 1J91_A,B 1F0Q_A 1DS5_A,B,C,D 4DGM_A 3MVJ_A,B,E 4DAW_A 1CMK_E 3NR9_A,B,C 1CDK_A,B 3NX8_A 1CTP_E 2BMC_A,B,C,D,E,F 2EU9_A 3RAW_A,B 2WU7_A 2WU6_A 2EXE_A 3VQH_A 3POO_A 3P0M_A 3FY0_A 3OXT_A 3OWP_A 3OVV_A 3OOG_A 3L9L_A,B 3AGM_A 3AGL_A,B 2GNL_A 2GNJ_A 1XH9_A 3FXZ_A 4EQC_A 2GNI_A 2GNH_A 2GNG_A 2GNF_A 3Q53_A 3Q52_A 1YDT_E 1YDS_E 1YDR_E 1SZM_A,B 2HY8_1 1Q61_A 1XHA_A 1SMH_A 4C38_A 4C37_A 4C36_A 4C35_A 4C34_A 4C33_A 1YHV_A 3Q4Z_A,B 2GCD_A,B 4FG8_A,B 2UZW_E 1U5R_A,B 2UZV_A 2UZU_E 2UZT_A 4IJ9_A 3KKV_A 3E8E_A,B,E,I,L,P 3E8C_A,B,C,D,E,F 3BWJ_A 1U5Q_A,B 2GFC_A 1XH8_A 1XH7_A 1XH6_A 1XH5_A 1XH4_A 1VEB_A 1SVH_A 1SVG_A 1SVE_A 2XIK_A 2F57_A,B 1STC_E 1Q8W_A 1Q8U_A 1Q8T_A 4IE9_A 3ZO4_A 3ZO3_A 3ZO2_A 3ZO1_A 3AG9_A,B 2VO7_A 2OJF_E 2OH0_E 2JDS_A 2F7Z_E 2F7X_E 2F7E_E 2C1B_A 2C1A_A 3DNE_A 3DND_A 4APP_A 2X4Z_A 2C30_A 4KS8_A 4KS7_A 4L67_A 2BVA_A,B 3CKX_A 2J0I_A 2CDZ_A 2Q0N_A 4FIJ_A 4FII_A 4FIH_A 4FIG_A,B 4FIF_A,B 4FIE_A,B 3SLS_A,B 3CKW_A 1A06_A 4GCJ_A 4EZ7_A 4EZ3_A 4ERW_A 4ANB_A 3SQQ_A 3S1H_A 3S0O_A 3S00_A 3RZB_A 3RPY_A 3RPV_A 3RPR_A 3RPO_A 3ROY_A 4AN9_A 3RNI_A 3RMF_A 3RM7_A 3RM6_A 3RKB_A 3RK9_A 3RK7_A 3RK5_A 3RJC_A 3RAL_A 4AN3_A 3RAK_A 3RAI_A 3RAH_A 3R9O_A 3R9N_A 3R9H_A 3R9D_A 3R8Z_A 3R8V_A 3R8U_A 4AN2_A 3R8P_A 3R8M_A 3R8L_A 3R83_A 3R7Y_A 3R7V_A 3R7U_A 3R7I_A 3R7E_A 3R73_A 3R71_A 3R6X_A 3R28_A 3R1Y_A 3R1S_A 3R1Q_A 3QZI_A 3QZH_A 3QZG_A 3QZF_A 3QXP_A 3QXO_A 3QX4_A 3QX2_A 3QWK_A 3QWJ_A 3QU0_A 3QTZ_A 3QTX_A 3QTW_A 3QTU_A 3QTS_A 3QTR_A 3QTQ_A 3QRU_A 3QRT_A 3QQL_A 3QQK_A 3QQJ_A 3QQH_A 3QQG_A 3QQF_A 3QL8_A 3PY1_A 3PY0_A 3PXZ_A 3PXY_A 3PXR_A 3PXQ_A 3PXF_A 3ZHP_C,D 4FGB_A 4FG9_A,B 1Q62_A 1Q24_A 2JC6_A,C 4AXA_A 2VO6_A 2VO3_A 2VO0_A 2VNY_A 2VNW_A 2UW8_A 2UW7_A 2UW6_A 2UW5_A 2UW4_A 2UW3_A 2UW0_A 2UVZ_A 2UVY_A 2UVX_A 2JDV_A 2JDT_A 4FG7_A 3MFU_A 3MFT_A 3MFS_A 3MFR_A 3I6W_A,B,C,D,E,F,G,H 3I6U_A,B 3IS5_A,B,C,D,E,F 4L3L_A 4L3J_A 3ZLY_A 2YAB_A,B 2YAA_A,B 2YA9_A,B 3A7J_A 3EQI_A 3EQH_A 3EQG_A 3EQF_A 4L44_A 4L43_A 4L46_A 4L45_A 1KOB_A,B 4BBM_A,B 4AAA_A 3EQD_A 3A62_A 3A61_A 3A60_A,B 2CKE_A,B,C,D 2A2A_A,B,C,D 1Z9X_A,B,C 4L42_A 3EQC_A 2Y7J_A,B,C,D 1WMK_A,B,C,D,E,F,G,H 2A27_A,B,C,D,E,F,G,H 3ZM4_A 1CM8_A,B 3ZLX_A 3ZLS_A 3C0I_A 3C0H_A,B 3C0G_A,B 1ZWS_A,B,C,D,E,F,G,H 3ZLW_A 3TAC_A 3A7I_A 2Y4I_C 2J90_A,B 3VUT_A,B 3ALO_A 3BQR_A 3BHY_A 1YRP_A,B 3ALN_A,B,C 2XUU_A 2W4J_A 4B4L_A 3VN9_A 2Y0A_A 1WVY_A 1WVX_A 1WVW_A 4EZ5_A 4AUA_A 3NUX_A 3NUP_A 3NDM_A,B,C,D 3NCZ_A,B,C,D 3D9V_A,B 2ETR_A,B 2ETK_A,B 2ESM_A,B 2X0G_A 2V55_A,C 3V8S_A,B,C,D 3TWJ_A,B,C,D 3TV7_A,B,C,D 3F5U_A 3F5G_A 3EHA_A 3EH9_A 1JKT_A,B 1JKS_A 1JKL_A 1JKK_A 1IG1_A 3ZXT_A,B,C,D 2YAK_A 2Y4P_A,B,C,D 2XZS_A,B 3DGK_A 3DFC_B 2W4K_A 1P4F_A 2F2C_B 2EUF_B 1XO2_B 1JOW_B 1G3N_A,E 1BLX_A 1BI8_A,C 1BI7_A	No
xLIR	431	436	GDYEFL	17 (2.2e-02)	Atg3_YEAST 268-273 (4)	4LGD_A,B,C,D	Yes

[+/-] Show/Hide Detailed ANCHOR results

DOMAIN	START	END	STATUS
ANCHOR1	254	262	hidden
ANCHOR2	276	301	hidden
ANCHOR3	327	373	hidden
ANCHOR4	391	401	hidden
ANCHOR5	432	440	hidden

[+/-] Show/Hide Detailed SMART results

DOMAIN	START	END	E-VALUE	TYPE	STATUS
SMART:S_TKc	30	281	4.2e-104	SMART	visible\|OK
Pfam:Pkinase_Tyr	30	278	2.4e-55	PFAM	hidden\|overlap
Pfam:Pkinase	30	281	1.5e-72	PFAM	hidden\|overlap
low_complexity_region	311	326	0	INTRINSIC	visible\|OK
Pfam:Mst1_SARAH	432	480	7.0e-30	PFAM	visible\|OK