iLIR v1.0 WWW Server: RESULTS PAGE

Submitted 1 sequence
>sp|O75385|ULK1_HUMAN Serine/threonine-protein kinase ULK1 OS=Homo sapiens GN=ULK1 PE=1 SV=2

{"length":"1050","regions":[{
startStyle: "curved", endStyle: "curved",
start: 16, end: 278, text: "S_TKc", colour: "#ff8800",
"metadata":{ database: "SMART", type: "S_TKc",
description: "S_TKc", start: 16, end: 278}
},
{
startStyle: "straight", endStyle: "straight",
start: 281, end: 317, text: "LCR", colour: "#86bcff",
"metadata":{ database: "INTRINSIC", type: "low_complexity_region",
description: "LCR", start: 281, end: 317}
},
{
startStyle: "straight", endStyle: "straight",
start: 340, end: 356, text: "LCR", colour: "#86bcff",
"metadata":{ database: "INTRINSIC", type: "low_complexity_region",
description: "LCR", start: 340, end: 356}
},
{
startStyle: "straight", endStyle: "straight",
start: 399, end: 425, text: "LCR", colour: "#86bcff",
"metadata":{ database: "INTRINSIC", type: "low_complexity_region",
description: "LCR", start: 399, end: 425}
},
{
startStyle: "straight", endStyle: "straight",
start: 583, end: 593, text: "LCR", colour: "#86bcff",
"metadata":{ database: "INTRINSIC", type: "low_complexity_region",
description: "LCR", start: 583, end: 593}
},
{
startStyle: "straight", endStyle: "straight",
start: 757, end: 769, text: "LCR", colour: "#86bcff",
"metadata":{ database: "INTRINSIC", type: "low_complexity_region",
description: "LCR", start: 757, end: 769}
},
{
startStyle: "straight", endStyle: "straight",
start: 775, end: 786, text: "LCR", colour: "#86bcff",
"metadata":{ database: "INTRINSIC", type: "low_complexity_region",
description: "LCR", start: 775, end: 786}
},
{
startStyle: "curved", endStyle: "curved",
start: 833, end: 1049, text: "Pfam:DUF3543", colour: "#ff8800",
"metadata":{ database: "PFAM", type: "Pfam:DUF3543",
description: "Pfam:DUF3543", start: 833, end: 1049}
},
{
startStyle: "straight", endStyle: "straight",
start: 355, end: 360, text: "xLIR", colour: "#ff00ff",
lineStyle: "bold", v_align: "top", label: "xLIR",
"metadata":{ database: "xLIR web server", type: "xLIR-motif",
description: "xLIR-motif:DDFVMV", start: 355, end: 360}
},
]
}

xLIR motifs are displayed as magenta rectangles in the domain architecture graphic

MOTIF	START	END	LIR sequence	PSSM score	Similar LIRs	In PDB	Anchor
xLIR	355	360	DDFVMV	19 (1.2e-02)	ATG13_HUMAN 442-447 (5) Q8MQJ7_DROME 389-394 (5) ULK1_HUMAN 355-360 (6) ULK2_HUMAN 351-356 (5)		Yes

[+/-] Show/Hide Detailed ANCHOR results

DOMAIN	START	END	STATUS
ANCHOR01	252	260	hidden
ANCHOR02	270	279	hidden
ANCHOR03	312	342	hidden
ANCHOR04	351	372	hidden
ANCHOR05	381	397	hidden
ANCHOR06	419	479	hidden
ANCHOR07	482	519	hidden
ANCHOR08	522	532	hidden
ANCHOR09	545	572	hidden
ANCHOR10	574	586	hidden
ANCHOR11	594	654	hidden
ANCHOR12	661	678	hidden
ANCHOR13	688	711	hidden
ANCHOR14	720	759	hidden
ANCHOR15	770	796	hidden
ANCHOR16	806	825	hidden

[+/-] Show/Hide Detailed SMART results

DOMAIN	START	END	E-VALUE	TYPE	STATUS
SMART:S_TKc	16	278	4.9e-96	SMART	visible\|OK
Pfam:Pkinase_Tyr	16	275	2.9e-52	PFAM	hidden\|overlap
Pfam:Pkinase	16	278	2.2e-69	PFAM	hidden\|overlap
Pfam:RIO1	24	150	2.0e-07	PFAM	hidden\|overlap
Pfam:Kdo	57	173	2.1e-07	PFAM	hidden\|overlap
low_complexity_region	59	71	0	INTRINSIC	hidden\|overlap
low_complexity_region	251	261	0	INTRINSIC	hidden\|overlap
low_complexity_region	281	317	0	INTRINSIC	visible\|OK
low_complexity_region	340	356	0	INTRINSIC	visible\|OK
low_complexity_region	399	425	0	INTRINSIC	visible\|OK
low_complexity_region	583	593	0	INTRINSIC	visible\|OK
low_complexity_region	757	769	0	INTRINSIC	visible\|OK
low_complexity_region	775	786	0	INTRINSIC	visible\|OK
Pfam:DUF3543	833	1049	7.7e-51	PFAM	visible\|OK