iLIR v1.0 WWW Server: RESULTS PAGE

Submitted 1 sequence
>sp|O14641|DVL2_HUMAN Segment polarity protein dishevelled homolog DVL-2 OS=Homo sapiens GN=DVL2 PE=1 SV=1

{"length":"736","regions":[{
startStyle: "curved", endStyle: "curved",
start: 11, end: 93, text: "DAX", colour: "#ff8800",
"metadata":{ database: "SMART", type: "DAX",
description: "DAX", start: 11, end: 93}
},
{
startStyle: "straight", endStyle: "straight",
start: 105, end: 124, text: "LCR", colour: "#86bcff",
"metadata":{ database: "INTRINSIC", type: "low_complexity_region",
description: "LCR", start: 105, end: 124}
},
{
startStyle: "curved", endStyle: "curved",
start: 160, end: 232, text: "Pfam:Dishevelled", colour: "#ff8800",
"metadata":{ database: "PFAM", type: "Pfam:Dishevelled",
description: "Pfam:Dishevelled", start: 160, end: 232}
},
{
startStyle: "straight", endStyle: "straight",
start: 250, end: 262, text: "LCR", colour: "#86bcff",
"metadata":{ database: "INTRINSIC", type: "low_complexity_region",
description: "LCR", start: 250, end: 262}
},
{
startStyle: "curved", endStyle: "curved",
start: 276, end: 355, text: "PDZ", colour: "#ff8800",
"metadata":{ database: "SMART", type: "PDZ",
description: "PDZ", start: 276, end: 355}
},
{
startStyle: "straight", endStyle: "straight",
start: 395, end: 407, text: "LCR", colour: "#86bcff",
"metadata":{ database: "INTRINSIC", type: "low_complexity_region",
description: "LCR", start: 395, end: 407}
},
{
startStyle: "curved", endStyle: "curved",
start: 433, end: 507, text: "DEP", colour: "#ff8800",
"metadata":{ database: "SMART", type: "DEP",
description: "DEP", start: 433, end: 507}
},
{
startStyle: "curved", endStyle: "curved",
start: 515, end: 726, text: "Pfam:Dsh_C", colour: "#ff8800",
"metadata":{ database: "PFAM", type: "Pfam:Dsh_C",
description: "Pfam:Dsh_C", start: 515, end: 726}
},
{
startStyle: "straight", endStyle: "straight",
start: 442, end: 447, text: "xLIR", colour: "#ff00ff",
lineStyle: "bold", v_align: "top", label: "xLIR",
"metadata":{ database: "xLIR web server", type: "xLIR-motif",
description: "xLIR-motif:RMWLKI", start: 442, end: 447}
},
]
}

xLIR motifs are displayed as magenta rectangles in the domain architecture graphic

MOTIF	START	END	LIR sequence	PSSM score	Similar LIRs	In PDB	Anchor
xLIR	442	447	RMWLKI	18 (1.6e-02)	DVL2_HUMAN 442-447 (6)	3ML6_A,B,C,D,E,F 1FSH_A	No

[+/-] Show/Hide Detailed ANCHOR results

DOMAIN	START	END	STATUS
ANCHOR01	53	63	hidden
ANCHOR02	77	92	hidden
ANCHOR03	110	117	hidden
ANCHOR04	123	147	hidden
ANCHOR05	151	162	hidden
ANCHOR06	172	207	hidden
ANCHOR07	227	234	hidden
ANCHOR08	260	282	hidden
ANCHOR09	513	518	hidden
ANCHOR10	545	557	hidden
ANCHOR11	567	586	hidden
ANCHOR12	593	605	hidden
ANCHOR13	614	643	hidden
ANCHOR14	650	685	hidden
ANCHOR15	702	736	hidden

[+/-] Show/Hide Detailed SMART results

DOMAIN	START	END	E-VALUE	TYPE	STATUS
low_complexity_region	3	12	0	INTRINSIC	hidden\|overlap
SMART:DAX	11	93	2.3e-56	SMART	visible\|OK
Pfam:DIX	11	93	1.4e-38	PFAM	hidden\|overlap
low_complexity_region	105	124	0	INTRINSIC	visible\|OK
Pfam:Dishevelled	160	232	1.9e-26	PFAM	visible\|OK
low_complexity_region	160	167	0	INTRINSIC	hidden\|overlap
low_complexity_region	193	208	0	INTRINSIC	hidden\|overlap
low_complexity_region	231	249	0	INTRINSIC	hidden\|overlap
low_complexity_region	250	262	0	INTRINSIC	visible\|OK
Pfam:PDZ	267	352	5.4e-22	PFAM	hidden\|overlap
SMART:PDZ	276	355	1.7e-15	SMART	visible\|OK
low_complexity_region	395	407	0	INTRINSIC	visible\|OK
SMART:DEP	433	507	6.6e-29	SMART	visible\|OK
Pfam:DEP	436	505	1.9e-19	PFAM	hidden\|overlap
Pfam:Dsh_C	515	726	8.5e-79	PFAM	visible\|OK
low_complexity_region	552	569	0	INTRINSIC	hidden\|overlap
low_complexity_region	572	606	0	INTRINSIC	hidden\|overlap
low_complexity_region	613	656	0	INTRINSIC	hidden\|overlap
low_complexity_region	661	672	0	INTRINSIC	hidden\|overlap
low_complexity_region	679	704	0	INTRINSIC	hidden\|overlap